The Tarim River Basin, located in the typical arid region, is one of the key regions of LUCC research in China and plays an important role in maintaining the sustainable development of the western China. In recent years,the ecological environment of the Tarim River Basin has degraded greatly. In the lower reaches, in particular, the riverbed has been dried up for more than 20 years, which accelerated the desertification and has been a great threat to people′s lives. Taking the section of the Tarim River between Qiala Lake and Taitema Lake as a typical region, an investigation on land cover changes was carried out with the support of remote sensing information of 1988 and 2000 respectively. The changes of land cover in this region were obtained: 1) Cropland tended to increase. 2) Urban or Built-up Area in 2000 was 324.4ha more than that in 1988. 3) Waters expanded by 3476.51ha. 4) Woodland and Grassland decreased, while Barren Land increased by 3824.9ha. The total amount of land use/land cover change between 1988 and 2000 is small,which is only 0.355% of the total area. It shows that the developmental pace of the lower reaches of the Tarim River is relative slow. Based on these results, the authors assessed the landscape dynamics of this region and pointed out that the degree of desertification was strengthened and the landscape dominated by sand land was further characterized by salt desert. The Tarim River Basin, located in the typical arid region, is one of the key regions of LUCC research in China and plays an important role in maintaining the sustainable development of the western China. In recent years, the ecological environment of the Tarim River Basin In the lower reaches, in particular, the riverbed has been dried up for more than 20 years, which accelerated the desertification and has been a great threat to people's lives. Taking the section of the Tarim River between Qiala Lake and Taitema Lake as a typical region, an investigation on land cover changes was carried out with the support of remote sensing information of 1988 and 2000 respectively. 2 The changes of land cover in this region were obtained: 1) Cropland tended to increase. 2) Urban or Built-up Area in 2000 was 324.4ha more than that in 1988. 3) Waters expanded by 3476.51ha. 4) Woodland and Grassland decreased, while Barren Land increased by 3824.9ha. The total amount of land use / l and cover change between 1988 and 2000 is small, which is only 0.355% of the total area. It shows that the developmental pace of the lower reaches of the Tarim River is relatively slow. Based on these results, the authors assessed the landscape dynamics of this region and pointed out that the degree of desertification was strengthened and the landscape dominated by sand land was further characterized by salt desert.