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目的:观察益母草注射液联合缩宫素预防产后出血的治疗效果。方法:将温州市中西医结合医院2008年1月～2010年12月100例足月妊娠经阴道自然分娩产妇随机平均分为研究组和对照组,对照组在胎头娩出后立即给予缩宫素10 U,肌肉注射或静滴;研究组在上述基础上联合益母草注射液,比较两组的产后出血并发症、子宫复旧情况。结果:二者联用,研究组第三产程所用时间明显短于对照组,产后2 h及24 h出血量也少于对照组(P<0.05),且产后出血的发生率也明显低于对照组(P<0.05),研究组用药过程中发生颜面潮红、血压升高及轻度胸部不适等并发症的发生率及新生儿窒息发生率明显低于对照组,研究组的子宫复旧程度明显优于对照组(P<0.05)。结论:益母草注射液与缩宫素对预防产后出血效果好,子宫复旧良好,并发症发生率低,优于单纯使用缩宫素。
Objective: To observe the effect of Motherwort injection combined with oxytocin in preventing postpartum hemorrhage. Methods: 100 cases of full-term vaginal spontaneous delivery of womb were randomly divided into study group and control group from January 2008 to December 2010 in Wenzhou Traditional Chinese and Western Medicine Hospital. The control group was given oxytocin 10 U, intramuscular injection or intravenous infusion; study group on the basis of the combination of motherwort injection, comparisons of postpartum hemorrhage complications, uterine involution. Results: The time spent on the third stage of labor in the study group was significantly shorter than that in the control group. The amount of bleeding at 2 and 24 h postpartum was also less than that of the control group (P <0.05), and the incidence of postpartum hemorrhage was significantly lower than that of the control group (P <0.05). The incidence of complications such as flushing, high blood pressure and mild chest discomfort and the incidence of neonatal asphyxia in study group were significantly lower than those in control group. The degree of uterine involution in study group was significantly superior In the control group (P <0.05). Conclusion: Motherwort injection and oxytocin are effective in preventing postpartum hemorrhage. Uterine involution is good and complication rate is lower than that of oxytocin alone.