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目的:分析总结肾移植术后恶性肿瘤的发病情况,探讨其临床特征和治疗措施。方法:回顾分析本院1978年～2009年间接受免疫抑制治疗(至少半年)的肾移植患者中发生恶性肿瘤的临床资料。结果:在1292例肾移植患者中共发现15例恶性肿瘤,发生率为1.16%。肾移植术后肿瘤患者1年存活率为73.33%,肾移植术后1年内死亡的4例,其中2例为移植肾输尿管恶性肿瘤,1例为肝癌,1例为移植肾恶性淋巴瘤。结论:肾移植术后恶性肿瘤是影响移植肾患者长期存活的严重并发症之一。肾移植术后患者需密切随访。
Objective: To analyze and summarize the incidence of malignant neoplasms after kidney transplantation and to discuss its clinical characteristics and treatment measures. Methods: The clinical data of malignant tumors in renal transplant patients receiving immunosuppressive therapy (at least six months) from 1978 to 2009 in our hospital were retrospectively analyzed. Results: A total of 15 malignant tumors were found in 1292 renal transplant recipients, with a prevalence of 1.16%. One-year survival rate of tumor patients after kidney transplantation was 73.33%, 4 patients died within 1 year after renal transplantation, 2 of them were transplanted renal cancer of ureter, 1 was liver cancer and 1 was malignant lymphoma of renal allograft. Conclusions: Malignant neoplasms are one of the serious complications that affect the long-term survival of transplant recipients. Patients after renal transplantation should be followed up closely.