Hepatocellular carcinoma (HCC) mostly develops in the liver under chronic inflammation.Oxygen radicals produced at the site of inflammation attack membrane
Circumventing antigen-specific self-tolerance in A2.1 transgenic mice allows the generation of A2.1-restricted TCR with high affnity for universal human tum
Intratumor BCG administration eradicates local as well as metastasized tumors.Administration of BCG into noncancerous tissues, however, results in no effect
A major limitation to the application of therapeutic monoclonal antibodies is their reduced in vivo efficacy compared to their high efficacy as measured in