A procedure is developed to incorporate seismic environment and site condition into the framework of seismic vulnerability estimation of building to consider the effects of the severity and/or frequency content of ground mo-tion due to seismic environment and site condition. Localized damage distribution can be strongly influenced by seismic environment and surficial soil conditions and any attempt to quantify seismic vulnerability of building should consider the impact of these effects. The seismic environment, site and structure are coupled to estimate damage probability distribution among different damage states for the building. Response spectra at rock site are estimated by probabilistic seismic hazard assessment approach. Based upon engineering representations of soil and amplifying spectral coordinates, frequency content and severity of ground motion are considered. Furthermore the impacts of severity and/or frequency of ground motion effects are considered to estimate the seismic response of reinforced concrete building and damage probability distribution for the building. In addition, a new method for presenting the distribution of damage is developed to express damage probability distribution for the building for different seismic hazard levels. A procedure is developed to incorporate seismicismic and site condition into the framework of seismic vulnerability estimation of building to consider the effects of the severity and / or frequency content of ground mo-tion due to seismic environment and site condition. Localized damage distribution can be strongly influenced by seismic environment and surficial soil conditions and any attempt to quantify seismic vulnerability of building should consider the impact of these effects. The seismic environment, site and structure are coupled to estimate damage probability distribution among different damage states for the building. Based upon engineering representations of soil and amplifying spectral coordinates, frequency content and severity of ground motion are considered. Furthermore the impacts of severity and / or frequency of ground motion effects are considered to estimate the seism ic response of reinforced concrete building and damage probability distribution for the building. In addition, a new method for presenting the distribution of damage is developed to express damage probability distribution for the building for different seismic hazard levels.