美国费城杰福逊大学医学院 Stein 研究中心主任,儿科主任教授 Brent RL 参加日本国际致畸会议后,于1988年7月18日至20日应邀在天津讲学,并参观指导天津市中心妇产科医院及其实验室。在津期间共讲6个题目:(1)胎儿宫内生长迟缓的临床表现,(2)肢体缺如的病因探讨;(3)药物及化学致畸剂研究的新进展;(4)化疗药物及放射线对妊娠的影响;(5)放射线对胚胎基因突变的影响;(6)新生儿皮肤病的诊断和处理,今简述于下。一、胎儿宫内生长迟缓的临床表现早产、胎儿宫内生长迟缓(IUGR)和出 Brent RL, director of the Stein Research Center at Jefferson University Medical School in Philadelphia, and professor of pediatrics, attended the International Teething Conference in Japan. From July 18 to July 20, 1988, Brent RL was invited to give lectures in Tianjin and to visit the obstetrics and gynecology department Hospital and its laboratories. A total of six topics in the period of Jin: (1) fetal intrauterine growth retardation of the clinical manifestations, (2) the etiology of limb absence; (3) drug and chemical teratogen research progress; (4) chemotherapy drugs And radiation on the impact of pregnancy; (5) radiation on the impact of embryonic mutations; (6) neonatal diagnosis and treatment of skin diseases, now outlined below. First, the clinical manifestations of fetal growth retardation Premature delivery, intrauterine growth retardation (IUGR) and out