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自的：探讨系统性红斑狼疮（ＳＬＥ）患者天然杀伤（ＮＫ）细胞数的改变。方法：采用免疫荧光法和流式细胞仪，对３８例ＳＬＥ患者及２０名正常人的天然杀伤细胞数进行检测。结果：活动期ＳＬＥ患者天然杀伤细胞为０．０７± ０．０４，其中２３例狼疮肾炎天然杀伤细胞为０．０５±０．０３，非狼疮肾炎天然杀伤细胞为０．１０±０．０３；治疗前、后天然杀伤细胞分别为０．０７±０．０３、０．１０±０．０４，组间及组内比较均Ｐ＜０．０１。结论：ＳＬＥ的发生可使天然杀伤细胞数下降。
From: To investigate the change of natural killer (NK) cells in patients with systemic lupus erythematosus (SLE). Methods: The number of natural killer cells in 38 SLE patients and 20 normal persons was detected by immunofluorescence and flow cytometry. Results: The number of natural killer cells in active SLE patients was 0.07 ± 0.04, of which 23 ± 0.05 ± 0.03 in natural killer cells of lupus nephritis and 0.10 ± 0.03 in non-lupus nephritis patients. The natural killer cells before and after treatment were 0.07 ± 0.03 and 0.10 ± 0.04, respectively, P <0.01 between groups and groups. Conclusion: The occurrence of SLE can reduce the number of natural killer cells.