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本文报告1992半1月~1996半12月本院外科30例胃癌根治性切除及术中,术后化疗的临床资料。其中贲门胃底癌9例,胃体癌7例,胃窦癌14例。行远端胃大部切除14例,近端胃大部切除术9例,全胃切除7例,联合脏器切除2例。术后均随访,其1,3、5早生存率分别为86%、64%、52%。术中及术后给予单药及联合化疗,经观察疗效好,提高了病人生存率。我们的体会是:胃癌一经确诊应及早手术,切除范围一定要足;术中化疗是防止肿瘤医源性播散的重要措施;术后化疗以尽早为宜,用药量要足,防止安慰性给药;联合化疗应注意药物的协同作用。
This article reports the clinical data of radical resection of gastric cancer and intraoperative and postoperative chemotherapy for 30 cases from 1992 to January 1996 to December 1996. Among them, there were 9 cases of cardiac gastric cancer, 7 cases of gastric body cancer, and 14 cases of gastric antrum cancer. The patients underwent distal gastrectomy in 14 cases, proximal gastrectomy in 9 cases, total gastrectomy in 7 cases and joint organ resection in 2 cases. All patients were followed up, and their early survival rates of 1, 3, and 5 were 86%, 64%, and 52%, respectively. Intraoperative and postoperative administration of single agents and combination chemotherapy showed good curative effect and improved patient survival. Our experience is: once the diagnosis of gastric cancer should be performed as soon as possible, the scope of resection must be sufficient; intraoperative chemotherapy is an important measure to prevent the iatrogenic spread of cancer; postoperative chemotherapy is appropriate as soon as possible, the amount of medication should be enough to prevent comfort to Drugs; combination chemotherapy should pay attention to the synergies of drugs.