论文部分内容阅读
目的探讨颅内顶端动脉瘤的血流动力学特点,分析动脉瘤生长、破裂的机制。方法选取5只兔颈动脉顶端动脉瘤模型,结合医学影像学资料,采用计算流体力学(CFD)有限元方法的软件,对兔颈动脉顶端动脉瘤的血流动力学行数值模拟,并对瘤颈、瘤壁等部位切应力大小随时间变化情况及分布进行分析。结果顶端动脉瘤在整个心动周期里切应力几乎都在迅速变化,变化时程与血流速度的变化时程一致,切应力主要存在于瘤颈,动脉瘤颈入口边界切应力0.21T达峰值,为0.83Pa;出口边界切应力0.32T达峰值,为0.38Pa;动脉瘤壁切应力接近于0。结论顶端动脉瘤瘤壁切应力是促进动脉瘤生长、扩大的可能原因之一。CFD数值模拟是一种反映动脉瘤血流动力学较好的方法。
Objective To investigate the hemodynamic characteristics of intracranial aortic aneurysms and analyze the mechanism of aneurysm growth and rupture. Methods The top carotid artery aneurysm models of 5 rabbits were selected and combined with medical imaging data. The CFD finite element method software was used to simulate the hemodynamics of the carotid artery aorta. Neck, tumor wall and other parts of the shear stress changes over time and distribution analysis. Results The shear stress of the apical aneurysm almost changed rapidly during the whole cardiac cycle. The change of the time course was consistent with the change of the blood flow velocity. The shear stress mainly existed in the neck of the aneurysm and the peak shear stress of the neck of the aneurysm was 0.21T, 0.83Pa; export boundary shear stress 0.32T peak, 0.38Pa; aneurysm wall shear stress close to 0. Conclusion The apical aneurysm wall shear stress is one of the possible reasons to promote the aneurysm growth and enlargement. CFD numerical simulation is a good way to reflect the aneurysm hemodynamics.