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目的观察急诊胃镜下止血联合奥美拉唑治疗上消化道溃疡出血患者的临床疗效。方法选取2015年4月-2017年4月在医院进行治疗的上消化道溃疡出血患者94例,随机分为观察组和对照组,每组47例。对照组患者在常规药物止血治疗的基础上给予奥美拉唑40 mg静脉滴注,持续7 d;观察组患者在对照组治疗的基础上加用急诊胃镜下止血治疗。评价2组患者的疗效,并统计其再出血率和转手术率。结果治疗后观察组患者疗效评价总有效率为93.62%(44/47)高于对照组的78.72%(37/47),差异有统计学意义(χ~2=4.3741,P<0.05)。观察组患者再出血率和转手术率均低于对照组,差异均有统计学意义(P<0.05)。结论急诊胃镜下止血联合奥美拉唑治疗上消化道溃疡出血患者不仅具有显著的治疗效果,而且再出血率和转手术率均较低,安全性高,值得临床上进一步推广应用。
Objective To observe the clinical efficacy of emergency endoscopy combined with omeprazole in patients with upper gastrointestinal ulcer bleeding. Methods 94 patients with upper gastrointestinal ulcer bleeding who were treated in hospital from April 2015 to April 2017 were randomly divided into observation group and control group, with 47 cases in each group. Patients in the control group were given omeprazole 40 mg intravenously on the basis of routine hemostatic treatment for 7 days. Patients in the observation group were treated with endoscopic emergency hemostasis on the basis of the control group. The efficacy of the two groups was evaluated, and the rate of rebleeding and the rate of surgery were also calculated. Results After treatment, the total effective rate in the observation group was 93.62% (44/47), which was significantly higher than that in the control group (78.72%, 37/47). The difference was statistically significant (χ ~ 2 = 4.3741, P <0.05). The rebleeding rate and the rate of operation in the observation group were lower than those in the control group, with significant differences (P <0.05). Conclusion Emergency endoscopy combined with omeprazole in patients with upper gastrointestinal ulcer bleeding not only has significant therapeutic effect, and the rate of rebleeding and surgery are lower, high safety, it is worth further clinical application.