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目的 评价腹腔镜下改良Soave’s法治疗新生儿先天性巨结肠(HD)术后近期功能.方法 对2005年6月至2011年05月确诊并腹腔镜下改良Soave’s法根治的新生儿HD(134例)行电话、信访和家访,随访1～6年.对复查的45例均行肛管直肠测压检查、腹部及肛门指诊检查,以期评价患儿术后近期功能.结果 本组术后大便次数正常者占71.9％(92/128),大便粘稠度正常者占80.4％(103/128),无污粪者占82.0％(105/128),排便紧迫期正常者占76.6％(98/128);术后1年能自主排便者占68.0％(87/128);直肠肛门抑制反射均未恢复,而主动收缩压(47±16.8)cm H2O、初感觉阈值较32～57ml均较正常儿童(41±13.4)cmH2O、18～58ml有所上升,但差异没有统计学意义(P＞0.05).失访率4.5％(6/134).结论 新生儿HD行腹腔镜下改良Soave’s法后多数患儿能达到社会可接受的排便功能.但术后直肠肛门抑制反射并未恢复,且需长期随访,及时处理并发症如小肠结肠炎、肛门狭窄等,对不同原因的排便障碍需进行主观和客观的评价.“,”Objective To investigate the postoperative intestinal function in newborn with Hirschsprung’s disease(HD) treated by laparoscopic operation.Methods From June 2005 to May 2011,134 newborn with HD who underwent modified laparoscopic Soave’s procedure were followed up by telephone,mails or home visit for 1 to 6 years.Forty-five patients were examined by anorectal manometry and abdominal and anal examination.The clinical progress and quality of life were recorded.Results Of all the patients,71.9％ (92/128) had normal frequency of stools,80.4％ (103/128) had normal stool consistency,82.0％ (105/128) had no soiling,76.6％ (98/128) had normal urgency period and 68.0％ (87/128) had the ability to control defecation.Although no rectal anal inhibitory reflex was positive in any of the patients postoperatively,the active contraction pressure (47 ± 16.8) cm H2O and early sensory threshold 32～57 ml were higher than those of normal children[(41 ± 13.4)cm H2O、18～38 ml],yet without significance (P＞0.05).The rate of loss of follow-up was 4.5％ (6/134).Conclusions Most of the patients have achieved an improved function of defecation after the modified laparoscopic Soave’s procedure in newborn with HD.In this short-term follow-up study,RAIR is not established in all patients postoperatively.