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虽已确证丙型肝炎可通过血液制品或血液污染传播,但多数散发的丙型肝炎感染与胃肠外的危险因素无关,而究竟通过怎样的非胃肠外方式获得感染尚不清楚.一种可能的非胃肠外传播方式是通过机体的分泌物.为了弄清这一方式的可能性,作者用高度敏感和特异的聚合酶链反应(PCR)方法对19例临床诊断为慢性非甲非乙型肝炎患者的分泌物作丙型肝炎病毒(HCV)RNA检测.这19例(男15例,女4例)患者均未接受过特殊的抗病毒治疗.采取患者血清、唾
Although it has been confirmed that hepatitis C can be transmitted by blood products or blood contamination, the majority of HCV infections are not associated with parenteral risk factors and it is unclear exactly what the parenteral route of infection is. The possible parenteral route of transmission is through the body’s secretions. To clarify the possibility of this approach, the authors used a highly sensitive and specific polymerase chain reaction (PCR) method to detect 19 cases of chronic non-A non-A Hepatitis B patient secretions were tested for hepatitis C virus (HCV) RNA, and none of the 19 patients (15 males and 4 females) received any antiviral treatment. Patient sera