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系统性红斑狼疮 (SLE)是一种常见的自身免疫性疾病，好发于中青年女性。患者外周血淋巴细胞在体外的自发凋亡速率较正常人明显加快，且与病情活动程度呈正相关 [1]，但外周血单一核细胞 (PBMC)凋亡加快的机理不明。近年研究发现 ,SLE患者血中脱氢表雄酮 (DHEA)水平降低，用 DHE
Systemic lupus erythematosus (SLE) is a common autoimmune disease that occurs in young women. The rate of spontaneous apoptosis of peripheral blood lymphocytes in patients was significantly higher than that in normal people, and positively correlated with the extent of disease activity [1]. However, the mechanism of accelerated apoptosis of peripheral blood mononuclear cells (PBMC) is unknown. Recent studies have found that blood levels of DHEA decreased in patients with SLE, with DHE