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目的:对QOL-RTI/H&N量表进行信度效度考核,以考评量表是否适合于鼻咽癌患者生存质量的测评。方法:收集中山大学肿瘤医院416例鼻咽癌患者的QOL-RTI/H&N和人口学资料,采用Cronbach’sα、相关分析、信度分析、证实性因子分析和方差分析考核量表的信度(α信度、分半信度和重测信度)、效度(结构效度)和区分度。结果:所有方面的Cronbach’sα系数和分半系数均>0.6,所有方面的重测系数均>0.7。总体模型的证实性因子分析显示,正规拟合指数、非正规拟合指数以及比较拟合指数都等于1,近似误差均方根RMSEA为0.000,95%RMSEA为(0.000;0.078)。不同放疗阶段的患者在所有方面的得分差异均有统计学意义(P<0.05),正在接受放疗患者的生存质量普遍较低。结论:QOL-RTI/H&N量表具有良好的信度、效度和区分度,可操作性强,可用于鼻咽癌患者的生存质量评价。
OBJECTIVE: To evaluate the reliability and validity of the QOL-RTI / H & N scale to assess whether the scale is suitable for evaluating the quality of life of patients with nasopharyngeal carcinoma. Methods: QOL-RTI / H & N and demographic data were collected from 416 patients with nasopharyngeal carcinoma at Sun Yat-sen University Cancer Hospital. Cronbach’s α, correlation analysis, reliability analysis, confirmatory factor analysis and analysis of variance were used to evaluate the reliability of the scale alpha reliability, half reliability and retest reliability), validity (structural validity), and discrimination. Results: The Cronbach’s alpha coefficient and the fractional half-coefficient were> 0.6 in all respects, and the retest coefficients were> 0.7 in all respects. Confirmatory factor analysis of the overall model showed that the normal fitting index, the non-normal fitting index and the comparative fitting index both were equal to 1, the root mean square error of the approximate error RMSEA was 0.000, and the 95% RMSEA was (0.000; 0.078). Patients in different stages of radiotherapy showed statistically significant differences in all aspects (P <0.05), and those receiving radiotherapy generally had lower quality of life. Conclusion: The QOL-RTI / H & N scale has good reliability, validity and discrimination, and it can be used in the evaluation of quality of life in patients with nasopharyngeal carcinoma.