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目的观察雷贝拉唑与克拉霉素及阿莫西林联合应用根除幽门螺杆菌(Hp)的疗效。方法选择符合条件的76例十二指肠溃疡患者,口服雷贝拉唑10mg、克拉霉素500mg与阿莫西林1g,每天2次,连续5d;第6天开始单独服用雷贝拉唑10mg,每天1次,共9d。治疗4周后,复查胃镜及Hp检查。结果76例中Hp转阴72例,Hp根除率为94.7%,愈合74例,愈合率97.4%。未发生严重副作用。结论雷贝拉唑三联短程疗法能有效根除Hp,治疗十二指肠溃疡疗效佳。
Objective To observe the efficacy of rabeprazole combined with clarithromycin and amoxicillin in the eradication of Helicobacter pylori (Hp). Methods A total of 76 patients with duodenal ulcer were selected. Rabeprazole 10 mg, clarithromycin 500 mg and amoxicillin 1 g were given orally twice daily for 5 days. Rabeprazole 10 mg was taken on the 6th day, 1 day, a total of 9d. After 4 weeks of treatment, repeat gastroscopy and Hp examination. Results Of the 76 cases, Hp was negative in 72 cases, the eradication rate of Hp was 94.7%, healing 74 cases, the healing rate was 97.4%. No serious side effects. Conclusion Rabeprazole triple short-term therapy can effectively eradicate Hp, the treatment of duodenal ulcer good effect.