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目的:观察安胎种子丸对不明原因复发性流产(URSA)患者封闭抗体和妊娠的影响。方法:将64例纳入病例随机分为中药治疗组33例和免疫治疗组31例。中药治疗组采用安胎种子丸治疗,免疫治疗组采用主动免疫治疗。2组均在治疗前后分别检测封闭抗体,观察妊娠情况。结果:2组妊娠成功率比较,差异无显著性意义(P>0.05)。2组封闭抗体转阳率比较,差异无显著性意义(P>0.05)。结论:中药安胎种子丸治疗URSA疗效肯定,能提高保护性抗体,调节母胎免疫;且其安全可靠,无明显毒副作用,价格低廉,适于推广应用。
Objective: To observe the effect of tianchizi pill on blocking antibody and pregnancy in patients with unexplained recurrent spontaneous abortion (URSA). Methods: Sixty-four cases were randomly divided into three groups: 33 cases in TCM group and 31 cases in immunotherapy group. Chinese medicine treatment group treated with tocolysis seed pills, immunotherapy group using active immunotherapy. Before and after treatment, the two groups were tested for blocking antibodies and observe the pregnancy. Results: There was no significant difference between the two groups in the success rate of pregnancy (P> 0.05). There was no significant difference between the two groups in the positive rate of blocking antibodies (P> 0.05). Conclusion: The Chinese medicine Triticum seed pills can treat URSA with certain curative effect. It can raise protective antibody and regulate the immunization of maternal fetus. And it is safe and reliable, has no obvious toxic and side effects, is low in price and suitable for popularization and application.