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目的寻求与膀胱移行细胞癌预告后相关的新诊断方法。方法以SABC免疫组化及亲和组化法研究83例膀胱移行细胞癌的血管内`皮细胞生长因子(VEGF)表达、微血管计数及其与病理分级。预后的关系。结果BEGF表达强度、微血管计数在Ⅲ与Ⅰ级癌间、在有复发、转移及5年死亡组与无复发、转移组间有极显著性差异(P<0.01)VEGF表达、微血管计数在Ⅲ级癌组、在有复发、转移及5年死亡组有相关性。结论VEGF是血管形成的重要因子。VEGF高级表达.微血管计数高是辅助预测膀胱癌患者预后不佳的新指标
Objective To search for a new diagnostic method related to the prognosis of bladder transitional cell carcinoma. Methods The expression of vascular endothelial growth factor (VEGF), microvessel count and pathological grade in 83 cases of transitional cell carcinoma of the bladder were studied by SABC immunohistochemistry and immunohistochemistry. Prognosis of the relationship. Results The expression of BEGF and the number of microvessel in grade Ⅲ and Ⅰ cancer were significantly different between recurrence and metastasis, 5-year death and non-recurrence and metastasis (P <0.01) Cancer group, there is recurrence, metastasis and 5-year death group were related. Conclusion VEGF is an important factor in angiogenesis. VEGF high expression. Microvascular count is high to predict the prognosis of bladder cancer patients with poor prognosis of new indicators