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①目的探讨胰岛素在高血压发病过程中的作用。②方法用放射免疫分析方法检测２８例原发性高血压病人血浆胰岛素含量变化，统计学处理采用ｔ检验。③结果原发性高血压病人血浆胰岛素含量比正常人明显增高（ｔ＝３．０２９，Ｐ＜０．０１）；原发性高血压伴左室肥厚者，其血浆胰岛素含量高于无左室肥厚者（ｔ＝４．６１８，Ｐ＜０．０１）；心电图Ｓ－Ｔ段下移、Ｔ波倒置的病人血浆胰岛素含量高于心电图正常者（ｔ＝２．６７８，Ｐ＜０．０５）。④结论胰岛素在原发性高血压发病中可能具有重要作用。
Objective To investigate the role of insulin in the pathogenesis of hypertension. Methods The radioimmunoassay method was used to detect plasma insulin levels in 28 patients with essential hypertension. The t test was used for statistical analysis. Results The plasma insulin levels in patients with essential hypertension were significantly higher than those in normal controls (t = 3.029, P <0.01). The plasma insulin levels in patients with essential hypertension and left ventricular hypertrophy were higher than those without left ventricular Patients with hypertrophy (t = 4.618, P <0.01) had higher plasma insulin levels than those with normal ECG (t = 2.678, P <0.05) . ④ Conclusion Insulin in the pathogenesis of essential hypertension may play an important role.