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目的 了解我区自 1 992年乙肝疫苗接种纳入计划免疫以来 ,4岁幼儿班及小学 1～ 6年级学生的乙肝疫苗免疫接种效果及乙肝感染情况。方法 采用酶联免疫法于 2 0 0 3年 8～ 1 0月对我区 4岁幼儿班及小学 1～ 6年级的学生进行 HBs Ag、抗 -HBs指标检测。结果 HBs Ag阳性率为 0 .64% ,其中 HBs Ag阳性率最高是小学六年级 ,阳性率为1 .1 2 % ,最低是 4岁幼儿班 ,阳性率为 0 .0 8% ;抗 -HBs阳性率为 66.2 5 %。结论 新生儿乙肝疫苗全程接种对提高人群免疫水平 ,降低乙肝病毒感染率起重要作用
Objective To understand the effect of hepatitis B vaccine immunization and hepatitis B infection in 4-year-old preschool children and students in grades 1 to 6 in our district since the hepatitis B vaccination was enrolled in the district in 1992. Methods HBsAg and anti-HBs were detected by enzyme-linked immunosorbent assay (ELISA) in 8-month-old children aged 4 to 6 years in our district from January to August in 2003. Results The positive rate of HBs Ag was 0.64%. The positive rate of HBs Ag was the sixth grade in primary school, the positive rate was 11.2%, the lowest was 4-year-old preschool children, the positive rate was 0.08%. The anti-HBs The positive rate was 66.2 5%. Conclusion The whole course vaccination of newborn hepatitis B vaccine plays an important role in raising the level of immunity and reducing the rate of hepatitis B virus infection