帕金森病在脑中的病理过程及运动性症状已经明确,但是疾病病因的相关细节及疾病的发展进程还非常模糊。帕金森病是如何发生的?重要性在帕金森病的症状发生前,神经元的损伤可能已经发生有20年之久。所以,在疾病获得临床诊断之时,改善疾病的治疗就太晚了。所了解的事实在运动性症状发生前,许多非运动性症状已出现很久了,其中包括睡眠障碍、嗅觉丧失以及便秘。但是科学家并不能判断有这些症状 Parkinson’s disease in the brain pathological process and motor symptoms have been clear, but the etiology of the disease details and disease progression is still very vague. How Parkinson’s Disease Occurs? IMPORTANCE Neuronal damage may have occurred 20 years before the onset of symptoms of Parkinson’s disease. So, when the disease is clinically diagnosed, it is too late to improve the treatment of the disease. What You Know Before the onset of motor symptoms, many non-motor symptoms have been around for a long time, including sleep disturbances, loss of smell and constipation. But scientists can not judge these symptoms