近10～15年来,卵巢生殖细胞恶性肿瘤的预后有了非常显著的改观.若仅行手术治疗或手术加放疗,其预后极差.只有纯粹的无性细胞瘤及某些未成熟性畸胎瘤可能预后较好.而由于用了联合化疗使得恶性生殖细胞肿瘤提高到接近于90%的生存率.对卵巢生殖细胞瘤最常用的联合化疗是长春新硷、放线菌素D及环磷酰胺(VAC)或氨甲喋呤、放线菌素D及苯丁酸氮芥(MACb).晚近还有其他一些联合化疗方案;包括顺铂、博莱霉素及长春新硷(PBV), The prognosis of ovarian germ cell malignancies has been significantly improved over the past 10 to 15 years, with a very poor prognosis if only surgery or surgery plus radiotherapy is performed. Only pure dysgerminoma and some immature teratomas May have a good prognosis.But due to the use of combination chemotherapy makes malignant germ cell tumors increased to nearly 90% survival rate. The most commonly used chemotherapy for ovarian germ cell tumor is vincristine, actinomycin D and cyclophosphamide (VAC) or methotrexate, actinomycin D, and chlorambucil (MACb). There are other combinations of chemotherapy available late; including cisplatin, bleomycin and vincristine (PBV)