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本文收集国内已报告的MG1458例临床资料进行统计分析,发现我国的MG具有下列一些特点:发病人数有逐年增加的趋势;儿童发病率较高;以眼肌麻痹为首发症状者其中单纯眼肌型占优势(52.7%);氨基糖甙类抗生素是诱发危象的一个主要因素(14.2%);不但可累及骨骼肌也可侵犯平滑肌(?)同样可引起中枢神经系统的免疫球蛋白和淋巴细胞亚群的异常;免疫疗法是我国治疗的一条新途径。
This article collected the domestic MG1458 reported clinical data for statistical analysis and found that our MG has the following characteristics: the number of patients with a trend of increasing year by year; children with a higher incidence of ophthalmoplegia as the first symptom in which the simple ocular muscle type (52.7%); aminoglycoside antibiotics is a major factor inducing crisis (14.2%); can not only affect the skeletal muscle can also affect the smooth muscle (?) Also can cause central nervous system immunoglobulin and lymphocytes Subgroup abnormalities; immunotherapy is a new way of treatment in our country.