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目的了解闽东地区戊型肝炎近年来的流行病学特征及临床表现、治疗及预后情况,为该地区戊型肝炎的预防及临床诊治提供参考。方法对福建医科大学附属闽东医院近5年收治的153份戊型肝炎病例资料进行统计分析。结果本组患者153例,中老年患者85例(55.55%),男多于女,夏秋季发病最多为98例(64.05%),城镇与农村患者之比1.10∶1,重叠肝炎病毒感染17例(11.11%),无家庭聚集现象。所有病例均有不同程度的疲乏及肝功能异常,其中,黄疸型肝炎128例(83.66%)。治疗以卧床休息、清淡及富营养饮食为主,本组病例均好转及治愈出院,无1例转为慢性或死亡,重叠感染、年老及重症肝炎患者黄疸消退时间明显延长。结论戊型肝炎的发病及临床特点,与性别、年龄、居住环境、原有肝炎病毒慢性感染等因素有一定的关系。加强公共卫生管理和教育,培养良好的个人饮食和卫生习惯,是预防戊型肝炎的重要措施。
Objective To understand the epidemiological characteristics, clinical manifestation, treatment and prognosis of hepatitis E in eastern Fujian in recent years and provide reference for the prevention and clinical diagnosis and treatment of hepatitis E in this area. Methods A total of 153 cases of hepatitis E in our hospital affiliated to Fujian Medical University in recent 5 years were analyzed statistically. Results There were 153 cases in this group and 85 cases (55.55%) in middle-aged and elderly patients. There were more males than females, with a maximum of 98 cases (64.05%) in summer and autumn, a ratio of 1.10:1 in urban and rural areas, 17 cases of overlapping hepatitis virus infection (11.11%), no family aggregation phenomenon. All cases had different degrees of fatigue and abnormal liver function, of which, jaundice hepatitis 128 cases (83.66%). Treatment in bed rest, light and nutritious diet, the group of patients were cured and discharged, no one was converted to chronic or death, overlapping infections, jaundice in elderly patients with severe and subsided significantly longer. Conclusion The incidence and clinical characteristics of hepatitis E have some relations with such factors as gender, age, living environment and chronic hepatitis B virus infection. Strengthening public health management and education and developing good personal diet and health habits are important measures to prevent hepatitis E.