患者女,22岁。因发热、尿频、尿痛2天伴腰痛就诊。血尿常规异常。诊为“尿路感染”。平素健康,无药物过敏史。氨苄青霉素皮试(-),予氨苄青霉素2.0加生理盐水40ml静注,3次/日,用药5天后自觉症状明显缓解后停用。改口服诺氟沙星0.2g,3次/日,首次服用后10分钟,患者出现头晕、心悸、胸闷、面色苍白、口唇发绀,血压由入院时14/10kPa降至11/7kPa,神志清楚,心率110次/分。疑为氨苄青霉素所致迟发性变态反应。即给氧、肾上腺素1mg皮下 Female patient, 22 years old. Due to fever, frequent urination, dysuria 2 days with low back pain treatment. Hematuria is abnormal. Diagnosis as “urinary tract infection.” Usually healthy, no history of drug allergy. Ampicillin skin test (-), to ampicillin 2.0 plus saline 40ml intravenously, 3 times / day, after 5 days of treatment subjective symptoms relieved significantly disabled. Change oral norfloxacin 0.2g, 3 times / day, 10 minutes after the first taking, patients with dizziness, palpitations, chest tightness, pale, lips cyanosis, blood pressure decreased from 14/10 kPa admission to 11 / 7kPa, conscious, Heart rate 110 beats / min. Suspected ampicillin-induced delayed allergic reaction. That oxygen, epinephrine 1mg subcutaneous