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随着糖尿病(DM)患者生存期延长,慢性合并症已成为死亡的主要原因。糖尿病肾病(DN)是糖尿病的常见病变,是糖尿病患者主要死亡原因之一。为了了解DM患者的血清肌红蛋白(Mb)含量变化,以及与其它肾功能指标间的关系。我们测定了45例糖尿病患者(包括27例糖尿病无肾病患者),现报告如下。 材料和方法 一、对象:糖尿病患者共45例,诊断标准根据实用内科学。 1.糖尿病无肾病组:27例(男11例,女16例);年龄55.44±14.18岁,均为Ⅱ型糖尿病。经检查血肌酐(Cr)、尿素氮(BUN)正常,并无脑及视网膜病变,其中2例伴有高血压病。 2.糖尿病肾病组:18例(男10例,女8例),年龄65.53±6.60岁,均为Ⅱ型糖尿病,其中13例血Cr升高(154.9～537.1μmol/L),15例血BUN升高(8.O～31.77mmool/L),2例因肾衰,呼衰、循环衰竭而死
As diabetes mellitus (DM) patients have prolonged survival, chronic comorbidities have become the leading cause of death. Diabetic nephropathy (DN) is a common disease of diabetes and is one of the major causes of death in diabetic patients. In order to understand the changes of serum Mb in DM patients and its relationship with other renal function parameters. We measured 45 cases of diabetic patients (including 27 cases of diabetic patients without nephropathy), are as follows. Materials and methods First, the object: A total of 45 patients with diabetes, diagnostic criteria based on practical internal medicine. 1. Diabetic nephropathy group: 27 cases (11 males and 16 females); age 55.44 ± 14.18 years, are type II diabetes. After examination of serum creatinine (Cr), urea nitrogen (BUN) normal, no brain and retinopathy, of which 2 cases were associated with hypertension. Diabetic nephropathy group: 18 cases (10 males and 8 females), aged 65.53 ± 6.60 years, all of which were type Ⅱ diabetes mellitus, including 13 cases of elevated serum Cr (154.9-537.1 μmol / L), 15 cases of blood BUN (8.O ~ 31.77mmool / L), 2 cases died of renal failure, respiratory failure, circulatory failure