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目的:探析雌激素联合甲硝唑阴道给药治疗萎缩性阴道炎的疗效。方法:选取2012年10月至2014年10月我院收治的96例萎缩性阴道炎患者为研究资料,平均分为对照组和观察组。对照组给予甲硝唑治疗,观察组给予雌激素联合甲硝唑阴道给药治疗,对两组患者的治疗有效率、不良反应发生率进行对比分析。结果:观察组患者的治疗有效率为97.92%,优于对照组的79.17%(P<0.05);观察组患者的不良反应发生率为4.16%,优于对照组的20.83%(P<0.05)。结论:采用雌激素联合甲硝唑阴道给药治疗萎缩性阴道炎的疗效较为显著,且副作用较小,值得在临床上推广和应用。
Objective: To investigate the efficacy of vaginal administration of estrogen combined with metronidazole in the treatment of atrophic vaginitis. Methods: A total of 96 patients with atrophic vaginitis treated in our hospital from October 2012 to October 2014 were selected as the research data, divided equally into the control group and the observation group. The control group was treated with metronidazole. The observation group was treated with vaginal administration of estrogen combined with metronidazole. The treatment efficiency and the incidence of adverse reactions were compared between the two groups. Results: The effective rate of treatment in observation group was 97.92%, which was superior to 79.17% in control group (P <0.05). The adverse reaction rate in observation group was 4.16%, which was better than that in control group (20.83%, P <0.05) . Conclusion: The treatment of atrophic vaginitis with estrogen combined with metronidazole vaginally is more effective and less side-effect. It is worth to be popularized and applied clinically.