本文介绍了两例先有性格改变,孤独、寡言、淡漠、退缩等强烈的情感障碍和意志障碍,后有多动不安、兴奋、徘徊等行为异常,幻觉、妄想的病例。由于这些精神症状而以精神病的诊断住院达10～20年之久。病程呈慢性进行性,神经症状和智能障碍逐渐加重。末期则出现汞中毒的神经症状:构音困难,共济失调,感觉障碍,肌张力降低,反射减弱等。根据脑的病理学所见,除小脑颗粒细胞 This article describes two cases of abnormal behavior, hallucinations and delusions after the first change of personality, solitary, non-assertive, apathetic, withdrawal and other strong affective disorder and will disorder, followed by restlessness, excitement, wandering and other delusions. As a result of these psychiatric symptoms and psychiatric diagnosis of hospitalization up to 10 to 20 years. Chronic progressive disease, neurological symptoms and mental retardation gradually increased. Neurological symptoms of mercury poisoning at the end stage: dysarthria, ataxia, sensory disturbances, decreased muscle tone, reflexes and so on. According to the brain pathology seen, in addition to cerebellar granulosa cells