论文部分内容阅读
目的:总结评价伽玛刀放射外科治疗颅内脑膜瘤的效果。方法:80例患者年龄16～81岁,平均52.20岁;男25例,女55例。病史0.5～168个月,平均34.86个月,中位时间为15个月。24例为手术后复发或残留,肿瘤容积为0.88～35.90ml,平均10.57ml。局麻下立体定向强化MRI定位。应用边缘剂量10～20Gy,平均14.27Gy。中心剂量22.5～40Gy,平均29.40Gy。等剂量线为40％～60％,平均49.43%。等中心数目2～16个,平均9.24个。结果:临床随访6～48个月,平均17.84个月,其中54例好转(67.50%),19例无变化(23.75%),7例恶化(8.75%)。影像学随访4～34个月,平均(14.31±8.54)个月,其中2例容积消失(2.50%),32例容积缩小(40.00%),41例容积无变化(51.25%),5例容积增大(6.25%)。中心强化降低46例(57.50%),肿瘤边界模糊26例(32.50%)。结论:伽玛刀治疗脑膜瘤创伤小,控制肿瘤生长,与外科治疗效果相当。
Objective: To summarize and evaluate the effect of gamma knife radiosurgery for intracranial meningioma. Methods: 80 patients aged 16 to 81 years, mean 52.20 years; 25 males and 55 females. A history of 0.5 to 168 months, an average of 34.86 months, the median time of 15 months. 24 cases of recurrence or residual after surgery, the tumor volume was 0.88 ~ 35.90ml, an average of 10.57ml. Localization of stereotactic MRI under local anesthesia. Application edge dose 10 ~ 20Gy, an average of 14.27Gy. Center dose 22.5 ~ 40Gy, an average of 29.40Gy. Isodose line is 40% to 60%, an average of 49.43%. The number of centers is 2 to 16, with an average of 9.24. Results: The average follow - up was 6 to 48 months (average 17.84 months), of which 54 cases improved (67.50%), 19 cases changed (23.75%) and 7 cases (8.75%) changed. Imaging was followed up for 4 to 34 months, with an average of (14.31 ± 8.54) months, of which 2 cases lost volume (2.50%), 32 cases reduced in size (40.00%), 41 cases showed no change in volume Increase (6.25%). 46 cases (57.50%) were reduced and 26 (32.50%) tumors were blurred. Conclusion: Gamma knife treatment of meningioma trauma, tumor growth control, and surgical treatment results.