患儿,男,7岁。因腹泻应用诺氟沙星100mg,口服两次后腹泻止,即出现双眼脸浮肿。体检:双眼脸浮肿,肿胀处皮肤不红、不痛、不痒,心肺未见异常,肾区无叩痛,腹部及双下肢无肿胀。尿量正常,查肝功、肾功正常,两次查小便常规正常。停用诺氟沙星,观察2天后眼脸浮肿消失,其他均无异常发现,考虑为诺氟沙星引起的血管神经性水肿。 Children, male, 7 years old. Application of norfloxacin due to diarrhea 100mg, oral diarrhea twice, that is, double eyelid face edema. Physical examination: both eyes face edema, swelling at the skin is not red, no pain, itch, no abnormal heart and lungs, no percussion pain in the kidney area, no swelling of the abdomen and lower extremities. Urine volume is normal, check liver function, normal kidney function, check urine two times normal. Stop using norfloxacin, 2 days after the observation of eyelid edema disappeared, the other were no abnormalities, consider norfloxacin-induced angioedema.