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一、答:D 题解:心功能不全并肝功能不良者,应首选口服地高辛治疗。洋地黄叶及洋地黄酊剂虽含有洋地黄毒甙,但口服后吸收不完全,对胃肠道有明显刺激,而且药物中所含有效成分也难以标准化,故现已少用。洋地黄毒甙是从洋地黄叶中提取的结晶体,其不仅可准确计算剂量,而且对胃肠道的刺激作用也极轻微,故可切代前两者。但是,洋地黄毒甙经胃肠道吸收后,其97%与血清蛋白结合,体内代谢主要在肝脏进行,故心功能不全并肝功不良者不宜首选。西地兰虽然经肾脏排泄,但口服吸收不
A, A: D solution: heart failure and liver dysfunction, should be the preferred oral digoxin treatment. Although digitalis and digitalis tincture contain digoxin, but after oral absorption is not complete, there is significant stimulation of the gastrointestinal tract, and the active ingredients contained in the drug is also difficult to standardize, it is now less used. Digoxigenin is a crystal extracted from digitalis leaves, which not only can accurately calculate the dose, but also stimulate the gastrointestinal tract is also very slight, it can be cut before the first two. However, after digoxin absorption by the gastrointestinal tract, its 97% and serum protein binding, the body’s metabolism is mainly carried out in the liver, so cardiac dysfunction and liver dysfunction should not be preferred. Although Cedilan is excreted by the kidneys, oral absorption is not