恶性肿瘤的化学治疗的基本原理是利用癌细胞较正常细胞更易受抗癌药损害的特点,控制药物的浓度和作用时间,在正常细胞尚可耐受的条件下,最大限度地杀伤癌细胞。目前恶性肿瘤的化疗有很大的进展,已从姑息性向根治性过渡。但由于现有的抗癌药多数选择性差、毒性较大、且大部分有免疫抑制作用,故对多数恶性肿瘤来说,单独应用化疗,尚不可能达到 The basic principle of chemotherapy for malignant tumors is to utilize the characteristics that cancer cells are more susceptible to anticancer drugs than normal cells and control the concentration and duration of the drugs to kill the cancer cells to the maximum extent under normal tolerable conditions. At present, there is great progress in the chemotherapy of malignant tumors, from palliative to radical transition. However, due to the poor selectivity and toxicity of the existing anticancer drugs, most of them have immunosuppressive effects. Therefore, for most malignant tumors, chemotherapy alone is still impossible to achieve