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目的 探讨子宫腺肌病与子宫肌瘤的临床特点及实验室检查的价值,提高子宫腺肌病的术前诊断率。方法 对比分析25 例子宫腺肌病患者和31 例子宫肌瘤患者的临床资料。结果 两组患者发病年龄及临床表现相近,但子宫腺肌病的痛经症状明显( P< 0.05) 。B 超的诊断符合率子宫肌瘤组和子宫腺肌病组分别为87.5 % 和60.0 % ,两者相比, 有明显差异( P< 0.01) 。子宫腺肌病组血清CA125 水平明显升高, 其阳性率为72.0 % , 显著高于子宫肌瘤组(阳性率为0)( P< 0.01), 而外周血性激素水平两组比较无统计学差异( P > 0.05) 。结论 子宫腺肌病和子宫肌瘤的鉴别诊断可依靠临床表现及B 超所见。血清CA125 水平的测定对提高子宫腺肌病的术前诊断率具有一定价值, 可常规应用, 而外周血性激素水平意义不大
Objective To investigate the clinical features and laboratory tests of adenomyosis and uterine fibroids, and improve the preoperative diagnostic rate of adenomyosis. Methods Clinical data of 25 patients with adenomyosis and 31 patients with uterine fibroids were compared and analyzed. Results The onset age and clinical manifestations of the two groups were similar, but dysmenorrhea symptoms of adenomyosis were significant (P < 0.05). The diagnostic accuracy of B-ultrasonography was 87.5 % and 60.0 % in the uterine myoma group and the adenomyosis group, respectively. There was a significant difference between the two groups (P < 0.01). The serum CA125 level in the adenomyosis group was significantly higher, with a positive rate of 72.0%, significantly higher than that of the uterine fibroids group (positive rate was 0) (P<0.01). The sex hormone levels in the peripheral blood were compared between the two groups. No statistical difference (P > 0.05). Conclusion The differential diagnosis of adenomyosis and uterine fibroids can depend on clinical manifestations and B-ultrasound findings. The determination of serum CA125 levels has a certain value in improving the preoperative diagnostic rate of adenomyosis, and can be routinely used, but the significance of peripheral blood sex hormone levels is not significant.