论文部分内容阅读
目的探讨胃肠道间质瘤(G IST)的临床特点。方法对1998~2004年收治的46例G IST病人的临床表现、手术处理及病理结果进行回顾性分析。结果46例均行手术治疗。病理诊断良性13例(28.3%),潜在恶性10例(21.7%),恶性23例(50%)。随访时间6个月至6年,7例出现远处转移或局部复发,10例死亡(其中9例为恶性G IST)。结论G IST缺乏特征性临床表现,术前确诊率较低,其确诊依赖病理结果。目前G IST的治疗仍以手术切除为主,对复发或远处转移者积极再次手术可延长生存期。
Objective To investigate the clinical features of gastrointestinal stromal tumors (G IST). Methods The clinical manifestations, surgical treatment and pathological findings of 46 patients with G IST admitted from 1998 to 2004 were analyzed retrospectively. Results 46 cases were treated surgically. The pathological diagnosis was benign in 13 cases (28.3%), potentially malignant in 10 cases (21.7%) and malignant in 23 cases (50%). Follow-up time ranged from 6 months to 6 years. Seven cases had distant metastasis or local recurrence, and 10 died (9 of them were malignant GST). Conclusions G IST lacks characteristic clinical manifestations and the preoperative diagnosis rate is low. The diagnosis depends on the pathological findings. The current G IST treatment is still mainly surgical resection, recurrence or distant metastasis who actively re-surgery can extend the survival.