目的分析无保护左主干(ULMCA)病变患者经皮介入治疗近期疗效。方法对20例经冠状动脉造影证实并行经皮冠状动脉介入治疗术(PCI)治疗的ULMCA病变患者,随访近期(4周)主要不良心脏事件(MACE)及疗效。结果 20例患者均成功置入支架,心肌梗死溶栓试验(TIMI)血流分级达Ⅲ级,无严重术中并发症,术后4周内无MACE发生,胸痛症状得到不同程度缓解。结论严格筛选病例前提下,ULMCA病变经皮介入治疗近期安全有效。 Objective To analyze the short-term effect of percutaneous interventional therapy in patients with unprotected left main trunk (ULMCA) lesions. Methods Twenty patients with ULMCA underwent percutaneous coronary intervention (PCI) confirmed by coronary angiography were followed up for the recent major adverse cardiac events (MACE) and the therapeutic effect. Results Twenty patients were successfully placed in the stent. TIMI flow grade was grade Ⅲ, no severe intraoperative complications were found. No MACE occurred within 4 weeks after operation. The symptoms of chest pain were relieved to some extent. Conclusion Strict screening of cases under the premise of percutaneous interventional treatment of ULMCA lesions safe and effective recently.