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呼吸道合胞病毒（ＲＳＶ）下呼吸道感染是婴幼儿发病较高、危害较大的一种呼吸系统疾病。其发病机制尚未完全明了．尚无特效防治措施，发病率高，重复感染常见，易继发反复咳喘、气道高反应性疾病。近年来研究表明，ＲＳＶ感染机制与细胞免疫紊乱密切相关，Ｔｈ亚群比例失调，功能紊乱介导了类似支气管哮喘样的免疫病理效应。本文就该病中Ｔｈ细胞亚群分泌的细胞因子──ＩＦＮ－γ、ＩＬ－４在ＲＳＶ下呼吸道感染中的改变及对ＩｇＥ的调节作用。
Respiratory syncytial virus (RSV) lower respiratory tract infection is a higher incidence of infants and young children, a more damaging respiratory disease. The pathogenesis is not yet fully understood. There is no effective prevention and treatment measures, the high incidence of repeated infections common, easy secondary repeated cough, airway hyperresponsiveness disease. In recent years, studies have shown that, RSV infection mechanism is closely related to cellular immune disorders, Th subsets imbalance, dysfunction mediated similar to the bronchial asthma-like immunopathological effects. This article on the Th cell subsets in the disease secretion of cytokines ─ ─ IFN-γ, IL-4 in RSV lower respiratory tract infection in the changes and regulation of IgE.