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依托咪酯已经广泛用于临床麻醉，具有独特的药理特点，尤其适用于创伤、休克等血流动力学不稳定的危重患者的麻醉，在心胸外科麻醉和老年患者麻醉中有独特的优势。依托咪酯具有扩张冠状动脉和脑保护作用，增加了在临床应用的广度。同时，依托咪酯对肾上腺皮质功能的影响也得到了进一步的研究，拓宽了其适应证，使它能更安全地应用于临床麻醉和镇静。“,”Etomidate is a unique drug used for clinical anesthetic induction for a long time ,especially for severe patients with unstable hemodynamics,such as trauma and shock.Etomidate has many advantages in cardiothoracic surgery anesthesia and geriatric anesthesia.It has the function of expanding coronary artery and cerebral protection,increasing the extent of its clinical application.At the same time,the effects of etomidate on adrenocortical function have been further studied,which expands its indications,so that it can be safely used in the clinical anesthesia and sedation.