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静脉血栓栓塞是一种常见病,但对此病处理的研究甚少。对苏格兰医师的调查发现尽管大多数医师用静脉肝素、随后用口服华法令治疗病人,但用两种制剂治疗的时间却有很大的差异。治疗时间愈长,出血和其它副作用的危险愈大。抗凝剂对巳确诊的小腿深部静脉血栓形成(DVT)或肺血栓栓塞(PTE)是否有益,仍不清楚。治疗DVT无全面的安慰剂对照试验报告。然而,在随机研究的最初报告中,研究人员发现经静脉造影证实的90名DVT病人,经传统的肝素(6天)加苯丙香豆素(3个月)治疗后,与运动加保泰松治疗相比,
Venous thromboembolism is a common disease, but little is known about the treatment of this disease. A survey of Scottish physicians found that although most physicians treated patients with intravenous heparin followed by oral warfarin, the duration of treatment with the two agents varied widely. The longer the treatment, the greater the risk of bleeding and other side effects. Whether anticoagulants are beneficial for diagnosed deep venous thrombosis (DVT) or pulmonary thromboembolism (PTE) is still unclear. There is no comprehensive placebo-controlled trial of DVT for treatment. However, in the original randomized study, the researchers found that 90 DVT patients who were confirmed by venography were treated with traditional heparin (6 days) plus phenyl coumarin (3 months) Compared with pine treatment,