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目的研究影响脑卒中后失语症患者自然恢复的相关因素。方法103例急性脑卒中后失语症患者分别于急性期及脑卒中后3月进行NIHSS、WAB和BDAE评估,记录患者的各项基本参数及常规检查。结果脑卒中后3月的NIHSS及AQ评分分别为(17.09±5.31)、(54.92±24.49)分较急性期(20.34±4.87)、(33.17±24.21)分明显改善(P<0.01);AQ与NIHSS评分均呈负相关(r=-0.478、-0.726、-0.805,P<0.01);恢复不良组年龄(76.28±8.58)岁大于恢复良好组(67.09±12.34)岁(P<0.01);恢复不良组合并房颤者(7/18)比例高于恢复良好组(8/85)(P<0.01);Logistic回归分析显示全面性失语的OR值为6.727(95%CI∶2.195~20.62)(P<0.01)。结论(1)脑卒中3月后大多数患者的语言功能明显改善;(2)年龄大、伴房颤的患者恢复差;(3)全面性失语在脑卒中后的各种类型失语中预后差。
Objective To study the factors that influence the natural recovery of aphasia patients after stroke. Methods 103 patients with acute post-stroke aphasia were evaluated NIHSS, WAB and BDAE respectively in acute phase and 3 months after stroke. The basic parameters and routine examination of the patients were recorded. Results The scores of NIHSS and AQ in March after stroke were significantly higher than those in acute phase (20.34 ± 4.87) and (33.17 ± 24.21), respectively (17.09 ± 5.31 and 54.92 ± 24.49, P <0.01) NIHSS score was negatively correlated (r = -0.478, -0.726, -0.805, P <0.01). The age of the poor recovery group (76.28 ± 8.58) was significantly higher than that of the recovery group (67.09 ± 12.34) (P <0.01) The logistic regression analysis showed that the OR of comprehensive aphasia was 6.727 (95% CI: 2.195-20.62) (P <0.01) P <0.01). Conclusions (1) The language function of most patients after 3 months of stroke was significantly improved. (2) Patients with large age and with atrial fibrillation recovered poorly. (3) Comprehensive aphasia had poor prognosis among various types of aphasia after stroke .