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探讨肿瘤患者血浆可溶性Ｐ－选择素（Ｐ－ｓｅｌｅｃｔｉｎ）检测的意义。方法用ＥＬＩＳＡ法检测１１６例不同肿瘤患者血浆中可溶性Ｐ－ｓｅｌｅｃｔｉｎ的含量。结果各组肿瘤患者血浆可溶性Ｐ－ｓｅｌｅｃｔｉｎ均明显高于正常人对照组（Ｐ＜０．０５或Ｐ＜０．０１）。结论肿瘤患者血浆可溶性Ｐ－ｓｅｌｅｃｔｉｎ含量与正常人有差异，检测可溶性Ｐ－ｓｅｌｅｃｔｉｎ有可能成为肿瘤辅助诊断的一项有价值的指标。
To explore the significance of plasma soluble P-selectin in tumor patients. Methods The levels of soluble P-selectin in plasma of 116 patients with different tumors were detected by ELISA. Results Plasma soluble P-selectin was significantly higher in each group than in normal controls (P<0.05 or P<0.01). Conclusions The level of soluble P-selectin in patients with tumors is different from that in healthy people. Detection of soluble P-selectin may be a valuable indicator for tumor-assisted diagnosis.