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目的探讨高渗盐水(3%)与利多卡因联合使用对颅内高压的治疗效果。方法选取2013年6月到2015年6月在我院治疗的由临床外伤性所致的颅内高压患者100例,并随机分为对照组和观察组,各50例,其中观察组采用高渗盐水(3%)与利多卡因联合治疗,对照组采用常规的甘露醇治疗。分别检测两组患者在用药前后的颅内压变化,以及治疗前后的脑补CT情况。结果观察组的总有效率远远高于对照组,差异显著,P<0.05,具有统计学意义。结论高渗盐水(3%)与利多卡因联合使用治疗颅内高压具有良好的效果,且无明显的不良反应,值得推广应用。
Objective To investigate the therapeutic effect of hypertonic saline (3%) combined with lidocaine on intracranial hypertension. Methods 100 cases of intracranial hypertension caused by clinical traumatic injury in our hospital from June 2013 to June 2015 were selected and randomly divided into control group and observation group with 50 cases in each group. Saline (3%) and lidocaine combination therapy, the control group using conventional mannitol treatment. The changes of intracranial pressure in both groups before and after treatment were detected, and the state of brain CT before and after treatment were also measured. Results The total effective rate of the observation group is much higher than that of the control group, the difference was significant, P <0.05, with statistical significance. Conclusion Combined use of hypertonic saline (3%) and lidocaine has a good effect on intracranial hypertension, and no obvious adverse reactions, which is worth popularizing and applying.