论文部分内容阅读
一氧化氮(NO)作为一种无机化合物,早为人们所熟知。但是,作为内皮源性松弛因子(EDRF)在疾病中的作用是近年来方认识到的。一些研究表明,NO在调节肾脏生理功能和介导一些泌尿系统疾病中起重要作用。 NO的基本生物学特点 (一)NO的产生生物体中NO主要来源于细胞合成,而非饮食中含氮食物的转化。NO的合成酶称为NO合成酶,系单加氧酶。根据NO合成酶性质不同,可分为两类。一类称原生酶或Ⅰ型合成酶,参与NO生理作用;另一类称诱生酶或Ⅱ型合成酶,
Nitric oxide (NO) is well known as an inorganic compound. However, the role of endothelium-derived relaxing factor (EDRF) in diseases has been recognized in recent years. Some studies have shown that NO plays an important role in regulating renal physiology and mediating some urological diseases. The basic biological characteristics of NO (a) the production of NO NO in the body mainly from cell synthesis, rather than diet conversion of nitrogen-containing foods. NO synthase known as NO synthase, Department of monooxygenase. According to the different nature of NO synthase, can be divided into two categories. A class called native enzyme or type Ⅰ synthase, involved in the physiological role of NO; the other known as induced enzyme or type Ⅱ synthase,