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为了探讨急性高原病的发病机理，本文观察了急性高原反应、高原肺水肿及同海拔健康者各10名支气管肺泡灌洗液的改变，发现肺水肿患者肺泡灌洗液中含有大量的蛋白质，红细胞及白细胞，同时也含有大量的免疫球蛋白（IgC、IgA、IgM）和补体C3、C4；而急性高原反应患者肺泡灌洗液改变同高原健康人相比无异常发现，提示高原肺水肿患者肺循环有“漏孔”存在，高原肺水肿是一种高渗性肺水肿。而急性高原反应发病中未有肺泡腔渗漏发现。
In order to explore the pathogenesis of acute altitude sickness, this paper observed the changes of acute altitude sickness, high altitude pulmonary edema and 10 bronchoalveolar lavage fluid with the same altitude, and found that pulmonary alveolus lavage fluid in patients with pulmonary edema contains a lot of protein, red blood cells And white blood cells, but also contains a large number of immunoglobulin (IgC, IgA, IgM) and complement C3, C4; and alveolar lavage fluid changes in patients with acute altitude sick compared with normal high altitude patients without abnormal findings suggest that pulmonary edema in patients with pulmonary circulation A “leak hole” exists, high altitude pulmonary edema is a hypertonic pulmonary edema. The incidence of acute altitude sickness without alveolar leak found.