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目的:探讨超声引导下经皮穿刺无水乙醇置换结合聚桂醇保留的改良硬化疗法治疗肝肾囊肿的疗效及不良反应。方法:回顾性分析我院2013年5月至2015年4月肝肾囊肿96例,随机分成3组,每组32例,分别采用超声引导下经皮穿刺抽液后聚桂醇直接保留(聚桂醇直接保留组)、超声引导下经皮穿刺抽液后无水乙醇反复多次灌洗后聚桂醇保留(灌洗聚桂醇保留组)及超声引导下经皮穿刺抽液后无水乙醇反复多次灌洗后无水乙醇保留(灌洗无水乙醇保留组)。观察临床治疗效果及不良反应。结果:聚桂醇直接保留组总有效率为75.00%(24/32)、不良反应发生率为3.13%(1/32);灌洗聚桂醇保留组总有效率为93.75%(30/32)、不良反应发生率为9.38%(3/32);灌洗无水乙醇保留组总有效率为90.63%(29/32),不良反应发生率为31.25%(10/32)。聚桂醇直接保留组与灌洗聚桂醇保留组总有效率比较差异有统计学意义(P<0.05),两组不良反应比较差异无统计学意义(P>0.05);灌洗聚桂醇保留组与灌洗无水乙醇保留组总有效率比较差异无统计学意义(P>0.05),不良反应发生率比较差异具有统计学意义(P<0.05)。结论:超声引导下经皮穿刺肝肾囊肿无水乙醇灌洗结合聚桂醇保留的改良疗法不仅疗效好,且不良反应发生率较低,是一种疗效确切及不良反应少的好方法,值得临床推广应用。
OBJECTIVE: To investigate the curative effect and adverse reactions of ultrasound-guided percutaneous puncture and absolute alcohol replacement combined with lauromacrogol retention in the treatment of hepatorenal cyst with modified sclerotherapy. Methods: A retrospective analysis of our hospital from May 2013 to April 2015, 96 cases of liver and kidney cysts were randomly divided into three groups of 32 cases, respectively, under the guidance of ultrasound-guided percutaneous puncture fluid retention of polyethylene glycol (poly Guiyang alcohol direct retention group), ultrasound-guided percutaneous puncture after draining ethanol repeated lauromacyl alcohol retention (lavage retention lauryl alcohol group) and ultrasound-guided percutaneous puncture after pumping water Repeated ethanol lavage after ethanol retention (lavaged ethanol retention group). Observation of clinical treatment and adverse reactions. Results: The total effective rate in the direct retention group was 75.00% (24/32) and the adverse reaction rate was 3.13% (1/32) in the direct retention group. The total effective rate was 93.75% (30/32 ). The incidence of adverse reactions was 9.38% (3/32). The total effective rate was 90.63% (29/32) in the group of lavaged ethanol and 31.25% (10/32) in the adverse reactions. There was significant difference between the two groups in the total effective rate of laurolactam retention group and laumenol lauryl retention group (P <0.05), and there was no significant difference between the two groups (P> 0.05) There was no significant difference in the total effective rate between the retention group and the lavaged ethanol retention group (P> 0.05). The incidence of adverse reactions was statistically significant (P <0.05). Conclusion: Ultrasound-guided percutaneous puncture of liver and kidney cysts with ethanol lavage combined with lauromacrogol retention is not only a good curative effect, and the incidence of adverse reactions is low, is a good effect and adverse reactions less good way, it is worth Clinical application.