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TPN和硫酸吗啡(MS)在重症病人的治疗中是常用药物。已知TPN可导致不同程度的细菌移位。MS又可使肠郁积并伴有细菌过度繁殖。本实验旨在研究两者联合用药对细菌移位的作用。实验将鼠随机分成4组:对照组、TPN组、TPN+MS组和TPN(含谷氨酰胺,Gln)+MS组。用药4天。TPN经中心静脉导管给予,MS通过皮下给予。小肠
TPN and morphine sulfate (MS) are commonly used in the treatment of critically ill patients. TPNs are known to cause varying degrees of bacterial translocation. MS can make the intestine and accompanied by bacterial overgrowth. The purpose of this experiment is to study the effect of combination of the two drugs on bacterial translocation. Rats were randomly divided into 4 groups: control group, TPN group, TPN + MS group and TPN (Glutamine-containing Gln) + MS group. Medication for 4 days. TPN is given via the central venous catheter and MS is administered subcutaneously. Small intestine