过去十几年的研究已证明，β肾上腺受体功能失调是造成和加重心衰的一个重要因素［１］，当β受体对激动剂反应性下降时，心肌收缩力下降，心功能降低［２］。但β受体功能失调的机制一直不明。近几年随着分子生物学技术的迅速发展，人们开始对受体的基因表达进行研究，初... Research over the past decade or so has demonstrated that dysfunction of the beta adrenal receptor is an important factor in the development and aggravation of heart failure [1], and when the beta receptor responds to agonists, myocardial contractility decreases and cardiac function decreases [ 2]. However, the mechanism of β-receptor dysfunction has been unclear. In recent years, with the rapid development of molecular biology technology, people began to study the gene expression of receptors, initially ...