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[目的]了解2000～2006年南通市人群戊型肝炎病毒(hepatitis E virus,HEV)感染状况。[方法]对来自南通市的12537例受检者血清样本采用ELISA法检测抗HEV IgG和抗HEV IgM,分析该人群中血清HEV抗体阳性率的变化趋势。[结果]2000～2003年南通市人群HEV感染率从20.03%逐步下降到4.85%,2003～2006年HEV感染率维持在4.40%左右的较低水平;不同年龄组人群中,15岁以下未成年人HEV感染率仅为1.39%,显著低于25～64岁成年人(平均为8.17%,P≤0.005);男女两性感染率差异无统计学意义。[结论]2000～2006年南通市HEV感染率逐渐下降并维持于较低水平,HEV感染率存在年龄差异,男女感染率基本相同。
[Objective] To understand the infection status of hepatitis E virus (HEV) in Nantong City from 2000 to 2006. [Method] The serum samples of 12,537 subjects from Nantong City were tested by ELISA for the detection of anti-HEV IgG and anti-HEV IgM. The trend of the positive rate of serum HEV antibody in this population was analyzed. [Results] The infection rate of HEV in Nantong population gradually decreased from 20.03% to 4.85% from 2000 to 2003, and the infection rate of HEV maintained at a relatively low level of 4.40% from 2003 to 2006. Among the different age groups, The infection rate of human HEV was only 1.39%, which was significantly lower than that of adults aged 25-64 (average 8.17%, P≤0.005). There was no significant difference in the infection rate between men and women. [Conclusion] From 2000 to 2006, the infection rate of HEV in Nantong City gradually decreased and remained at a low level. The infection rate of HEV varied with age. The infection rates of men and women were basically the same.