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目的了解甘肃省天祝藏族自治县(天祝县)人群乙型肝炎(乙肝)病毒表面抗原(HBsAg)携带状况。方法开展全人群HBsAg携带、乙肝疫苗(HepB)接种率调查,儿童HepB接种免疫效果血清学检测。结果全人群HBsAg阳性率为3.08%;1～4岁、5～14岁儿童HBsAg阳性率分别为0.83%和2.27%;男、女HBsAg阳性率分别为3.57%和2.55%;城镇、农村HBsAg阳性率分别为1.30%和3.83%。结论天祝县1～14岁儿童HBsAg阳性率明显降低,表明自1992年将HepB纳入儿童计划免疫管理后,免疫效果显著。
Objective To understand the carrier status of hepatitis B virus surface antigen (HBsAg) in Tianzhu Tibetan Autonomous County (Tianzhu County) of Gansu Province. Methods To carry out whole population HBsAg carrier, hepatitis B vaccine (HepB) inoculation rate survey, children HepB vaccination effect of serological test. Results The positive rate of HBsAg in the whole population was 3.08%. The positive rate of HBsAg in children aged 1-4 was 5.83% and 2.27% respectively. The positive rates of HBsAg in male and female were 3.57% and 2.55% respectively. The positive rate of HBsAg in urban and rural areas was Rates were 1.30% and 3.83% respectively. Conclusion The positive rate of HBsAg in children aged 1 ~ 14 years in Tianzhu County was significantly lower than that in other provinces. The results showed that the immunization effect of HepB was included in the immunization program of children since 1992.