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目的探讨老年医院重症监护病房患者下呼吸道感染病原菌分布的特点及耐药情况。方法回顾性总结和分析医院2006年8月-2007年9月重症监护病房下呼吸道感染患者痰标本分离的111株病原菌及耐药性。结果98例感染者共分离出病原菌数111株,以革兰阴性杆菌为主,78株,占70.27%;革兰阴性杆菌中,铜绿假单胞菌位居第1位,23株,占20.72%;在革兰阳性杆菌中,除亚胺培南外,对其他抗菌药物耐药率较高,且表现多药耐药性。结论老年医院重症监护病房患者下呼吸道感染主要是以革兰阴性杆菌为主,病原菌显示多药耐药性,因此,临床应根据药敏结果科学合理地选择抗菌药物。
Objective To investigate the characteristics and drug resistance of pathogenic bacteria in lower respiratory tract infection in elderly hospital intensive care unit patients. Methods The clinical isolates and drug resistance of 111 pathogens isolated from the sputum of patients with lower respiratory tract infections in the intensive care unit from August 2006 to September 2007 in our hospital were retrospectively summarized and analyzed. Results A total of 111 strains of pathogens were isolated from 98 infected patients, mainly Gram-negative bacilli, 78 strains, accounting for 70.27%. Of the Gram-negative bacilli, Pseudomonas aeruginosa was the first, 23 strains accounting for 20.72 %; Gram-positive bacilli, in addition to imipenem, the higher rate of resistance to other antibiotics, and the performance of multi-drug resistance. Conclusion The lower respiratory tract infection in elderly hospital intensive care unit is mainly Gram-negative bacilli, and the pathogens show multi-drug resistance. Therefore, antibiotics should be scientifically and reasonably selected according to the drug susceptibility results.