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目的:探讨人参四逆汤加味治疗不同类型实体瘤患儿化疗不良反应的临床效果分析。方法:将2015年1月—2016年6月在本院儿科治疗的80例不同类型实体瘤患儿随机分为两组,均采用化疗治疗的方法,出现化疗不良反应,对照组采用西医常规治疗的方法,在此基础上观察组采用人参四逆汤加味治疗,6个月后比较两组患儿疲乏、恶心呕吐、纳差、白细胞低下等不良反应的改善情况、外周血象各指标、化疗依从性以及生活质量。结果:观察组治疗后疲乏、恶心呕吐、纳差、体重减轻、脱发等不良反应明显较对照组减轻,差异有统计学意义(P<0.05);观察组治疗后白细胞计数、血小板计数、血红蛋白浓度明显高于对照组,差异有统计学意义(P<0.05);观察组化疗依从性及化疗完成率均高于对照组,差异有统计学意义(P<0.05);观察组治疗后生活质量改善情况明显优于对照组,差异有统计学意义(P<0.05)。结论:人参四逆汤加味治疗不同类型实体瘤患儿化疗不良反应的临床效果显著,有效减轻化疗对机体的损伤,增强耐受性,提高生活质量,具有积极的临床意义。
Objective: To investigate the clinical effects of modified Ginseng and Sini decoction on the adverse reactions of chemotherapy in children with different types of solid tumors. Methods: From January 2015 to June 2016 in our hospital pediatric treatment of 80 patients with different types of solid tumors were randomly divided into two groups, were treated with chemotherapy, the emergence of adverse reactions to chemotherapy, the control group treated with conventional Western medicine On the basis of the observation group treated with modified Ginseng Sini Decoction, 6 months after the two groups of children with fatigue, nausea and vomiting, anorexia, leukopenia and other adverse reactions to improve the peripheral blood as indicators, chemotherapy compliance Sex and quality of life. Results: The adverse reactions such as fatigue, nausea, vomiting, anorexia, weight loss and hair loss in the observation group were significantly lower than those in the control group (P <0.05). The white blood cell count, platelet count, hemoglobin concentration (P <0.05). The compliance of chemotherapy and completion rate of chemotherapy in the observation group were higher than those in the control group (P <0.05), and the quality of life in the observation group was improved after treatment The situation was significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion: The clinical effect of modified Ginseng and Sini Decoction in treating children with different types of solid tumors is significant. It has a significant clinical effect of reducing the damage to the body, enhancing the tolerance and improving the quality of life.