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目的 观察胃癌患者红细胞免疫功能变化 ,探讨红细胞免疫功能异常在胃癌发生中的作用。方法 胃癌患者 30例 (均经内镜活检病理证实 ) ,检测其外周血红细胞C3b受体花环率 (RCR)、红细胞免疫复合物花环率 (RICR)、血清红细胞C3b受体花环促进率 (RFER)和抑制率 (RFIR) ,并与 30例健康成人对照分析。结果 胃癌患者RCR和RFER明显低于正常人 (P <0 .0 1) ,而RICR、RFIR则高于正常对照 (P <0 .0 1)。 结论 胃癌患者红细胞免疫功能存在明显异常
Objective To observe the changes of erythrocyte immune function in patients with gastric cancer and to explore the role of erythrocyte immune dysfunction in the occurrence of gastric cancer. Methods Thirty patients with gastric cancer (all confirmed by endoscopic biopsy) were examined for RBC, RICR and RFER of peripheral blood erythrocyte C3b receptor And inhibition rate (RFIR), and with 30 healthy adults control analysis. Results The RCR and RFER of gastric cancer patients were significantly lower than those of normal controls (P <0.01), but RICR and RFIR were higher than those of normal controls (P <0.01). Conclusion There are obvious abnormalities of erythrocyte immune function in patients with gastric cancer